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Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation

BACKGROUND AND OBJECTIVES: The neonatal and juvenile human kidney can be exposed to a variety of potentially toxic drugs (e.g., nonsteroidal anti-inflammatory drugs, antibiotics, antivirals, diuretics), many of which are substrates of the kidney organic anion transporters, OAT1 (SLC22A6, originally...

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Detalhes bibliográficos
Publicado no:Clin J Am Soc Nephrol
Main Authors: Momper, Jeremiah D., Yang, Jin, Gockenbach, Mary, Vaida, Florin, Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450358/
https://ncbi.nlm.nih.gov/pubmed/30885911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.10350818
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