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Functional Maturation of Drug Transporters in the Developing, Neonatal, and Postnatal Kidney

Because renal function in newborns is immature, the pharmacokinetics of drugs administered to neonates vary significantly from adult patients. The establishment of drug transport systems is a key process in the functional maturation of the nephron. However, a thorough examination of the expression o...

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Detalhes bibliográficos
Main Authors: Sweeney, Derina E., Vallon, Volker, Rieg, Timo, Wu, Wei, Gallegos, Thomas F., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127534/
https://ncbi.nlm.nih.gov/pubmed/21493727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070680
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