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Pharmacokinetics/pharmacodynamics of lefamulin in a neutropenic murine pneumonia model with Staphylococcus aureus and Streptococcus pneumoniae

OBJECTIVES: To present results of preclinical studies that supported further development of lefamulin for treating patients with community-acquired bacterial pneumonia (CABP). METHODS: The effect of bovine lung surfactant on the antibacterial activity of lefamulin against Streptococcus pneumoniae an...

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Publicado en:J Antimicrob Chemother
Main Authors: Wicha, Wolfgang W, Strickmann, Dirk B, Paukner, Susanne
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449573/
https://ncbi.nlm.nih.gov/pubmed/30949707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz086
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