Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model

Por Fischer, Evelin, Kappes, Barbara C, Wicha, Wolfgang W
Publicado no Open Forum Infect Dis (2017)

Pharmacokinetics/pharmacodynamics of lefamulin in a neutropenic murine pneumonia model with Staphylococcus aureus and Streptococcus pneumoniae

Por Wicha, Wolfgang W, Strickmann, Dirk B, Paukner, Susanne
Publicado no J Antimicrob Chemother (2019)

In vivo pharmacodynamics of lefamulin, the first systemic pleuromutilin for human use, in a neutropenic murine thigh infection model

Por Wicha, Wolfgang W, Craig, William A, Andes, David
Publicado no J Antimicrob Chemother (2019)

Prediction of lefamulin epithelial lining fluid penetration after intravenous and oral administration using Phase 1 data and population pharmacokinetics methods

Por Zhang, Li, Wicha, Wolfgang W, Bhavnani, Sujata M, Rubino, Christopher M
Publicado no J Antimicrob Chemother (2019)

Pharmacokinetics and tolerability of lefamulin following intravenous and oral dosing

Por Wicha, Wolfgang W, Prince, William T, Lell, Claudia, Heilmayer, Werner, Gelone, Steven P
Publicado no J Antimicrob Chemother (2019)

LB6. Oral Lefamulin Is Safe and Effective in the Treatment of Adults With Community-Acquired Bacterial Pneumonia (CABP): Results of Lefamulin Evaluation Against Pneumonia (LEAP 2)...

Por Alexander, Elizabeth, Goldberg, Lisa, Das, Anita, Moran, Gregory J, Sandrock, Christian, Gasink, Leanne B, Spera, Patricia, Sweeney, Carolyn, Paukner, Susanne, Wicha, Wolfgang W, Schranz, Jennifer
Publicado no Open Forum Infect Dis (2018)

Pharmacokinetic/pharmacodynamic target attainment analyses to support intravenous and oral lefamulin dose selection for the treatment of patients with community-acquired bacterial...

Por Bhavnani, Sujata M, Zhang, Li, Hammel, Jeffrey P, Rubino, Christopher M, Bader, Justin C, Sader, Helio S, Gelone, Steven P, Wicha, Wolfgang W, Ambrose, Paul G
Publicado no J Antimicrob Chemother (2019)