Pharmacokinetics and tolerability of lefamulin following intravenous and oral dosing

OBJECTIVES: To explore the pharmacokinetics (PK) of oral and intravenous (iv) lefamulin after single and multiple doses, and the effect of food on bioavailability. METHODS: Lefamulin PK was examined in four studies. In Study 1, PK was assessed in patients with acute bacterial skin and skin structure...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Wicha, Wolfgang W, Prince, William T, Lell, Claudia, Heilmayer, Werner, Gelone, Steven P
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Supplement Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449572/
https://ncbi.nlm.nih.gov/pubmed/30949704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz087
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