Distinct metabolic patterns during microglial remodeling by oleate and palmitate

Microglial activation by oleate and palmitate differentially modulates brain inflammatory status. However, the metabolic reprogramming supporting these reactive phenotypes remains unknown. Employing real-time metabolic measurements and lipidomic analysis, we show that both fatty acids promote microg...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://ncbi.nlm.nih.gov/pubmed/30867255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190072
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