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Distinct metabolic patterns during microglial remodeling by oleate and palmitate

Microglial activation by oleate and palmitate differentially modulates brain inflammatory status. However, the metabolic reprogramming supporting these reactive phenotypes remains unknown. Employing real-time metabolic measurements and lipidomic analysis, we show that both fatty acids promote microg...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://ncbi.nlm.nih.gov/pubmed/30867255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190072
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