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Cell Culture Models of Fatty Acid Overload: Problems and Solutions

High plasma levels of fatty acids occur in a variety of metabolic diseases. Cellular effects of fatty acid overload resulting in negative cellular responses (lipotoxicity) are often studied in vitro, in an attempt to understand mechanisms involved in these diseases. Fatty acids are poorly soluble, a...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Alsabeeh, Nour, Chausse, Bruno, Kakimoto, Pamela A., Kowaltowski, Alicia J., Shirihai, Orian
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969525/
https://ncbi.nlm.nih.gov/pubmed/29155055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2017.11.006
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