Distinct metabolic patterns during microglial remodeling by oleate and palmitate

Microglial activation by oleate and palmitate differentially modulates brain inflammatory status. However, the metabolic reprogramming supporting these reactive phenotypes remains unknown. Employing real-time metabolic measurements and lipidomic analysis, we show that both fatty acids promote microg...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Main Authors: Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2019
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://ncbi.nlm.nih.gov/pubmed/30867255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190072
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