Distinct metabolic patterns during microglial remodeling by oleate and palmitate

Microglial activation by oleate and palmitate differentially modulates brain inflammatory status. However, the metabolic reprogramming supporting these reactive phenotypes remains unknown. Employing real-time metabolic measurements and lipidomic analysis, we show that both fatty acids promote microg...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://ncbi.nlm.nih.gov/pubmed/30867255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190072
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