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Deciphering the role of trehalose in hindering antithrombin polymerization
Serine protease inhibitors (serpins) family have a complex mechanism of inhibition that requires a large scale conformational change. Antithrombin (AT), a member of serpin superfamily serves as a key regulator of the blood coagulation cascade, deficiency of which leads to thrombosis. In recent years...
Shranjeno v:
| izdano v: | Biosci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Portland Press Ltd.
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6449516/ https://ncbi.nlm.nih.gov/pubmed/30886063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20182259 |
| Oznake: |
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