Serpin Inhibition Mechanism: A Delicate Balance between Native Metastable State and Polymerization

The serpins (serine proteinase inhibitors) are structurally similar but functionally diverse proteins that fold into a conserved structure and employ a unique suicide substrate-like inhibitory mechanism. Serpins play absolutely critical role in the control of proteases involved in the inflammatory,...

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Detalhes bibliográficos
Main Authors: Khan, Mohammad Sazzad, Singh, Poonam, Azhar, Asim, Naseem, Asma, Rashid, Qudsia, Kabir, Mohammad Anaul, Jairajpuri, Mohamad Aman
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268027/
https://ncbi.nlm.nih.gov/pubmed/22312466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/606797
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