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Serpin Inhibition Mechanism: A Delicate Balance between Native Metastable State and Polymerization
The serpins (serine proteinase inhibitors) are structurally similar but functionally diverse proteins that fold into a conserved structure and employ a unique suicide substrate-like inhibitory mechanism. Serpins play absolutely critical role in the control of proteases involved in the inflammatory,...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE-Hindawi Access to Research
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268027/ https://ncbi.nlm.nih.gov/pubmed/22312466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/606797 |
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