The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

Follicular helper T cells (TFH cells), known as the primary “helpers” of the germinal center (GC) reaction, promote the humoral immune response to defend against various pathogens. Under conditions of infection by different types of pathogens, many shared transcription factors (TFs), such as Bcl-6,...

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Udgivet i:Front Immunol
Main Authors: Wang, Pengcheng, Wang, Youping, Xie, Luoyingzi, Xiao, Minglu, Wu, Jialin, Xu, Lifan, Bai, Qiang, Hao, Yaxing, Huang, Qizhao, Chen, Xiangyu, He, Ran, Li, Baohua, Yang, Sen, Chen, Yaokai, Wu, Yuzhang, Ye, Lilin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449430/
https://ncbi.nlm.nih.gov/pubmed/30984183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00606
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