The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

Follicular helper T cells (TFH cells), known as the primary “helpers” of the germinal center (GC) reaction, promote the humoral immune response to defend against various pathogens. Under conditions of infection by different types of pathogens, many shared transcription factors (TFs), such as Bcl-6,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wang, Pengcheng, Wang, Youping, Xie, Luoyingzi, Xiao, Minglu, Wu, Jialin, Xu, Lifan, Bai, Qiang, Hao, Yaxing, Huang, Qizhao, Chen, Xiangyu, He, Ran, Li, Baohua, Yang, Sen, Chen, Yaokai, Wu, Yuzhang, Ye, Lilin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449430/
https://ncbi.nlm.nih.gov/pubmed/30984183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00606
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