Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes

AIMS/HYPOTHESIS: Microvascular complications in the heart and kidney are strongly associated with an overall rise in inflammation. Annexin A1 (ANXA1) is an endogenous anti-inflammatory molecule that limits and resolves inflammation. In this study, we have used a bedside to bench approach to investig...

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Bibliografske podrobnosti
izdano v:Diabetologia
Main Authors: Purvis, Gareth S. D., Chiazza, Fausto, Chen, Jianmin, Azevedo-Loiola, Rodrigo, Martin, Lukas, Kusters, Dennis H. M., Reutelingsperger, Chris, Fountoulakis, Nikolaos, Gnudi, Luigi, Yaqoob, Muhammed M., Collino, Massimo, Thiemermann, Christoph, Solito, Egle
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448955/
https://ncbi.nlm.nih.gov/pubmed/29085990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4469-y
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