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Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells
Due to their ability to preferentially induce cell death in tumor cells, while sparing healthy cells, TNF-related apoptosis-inducing ligand (TRAIL) and agonistic anti-TRAIL-R1 or anti-TRAIL-R2-specific antibodies are under clinical investigations for cancer-treatment. However, TRAIL-Rs may also indu...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448923/ https://ncbi.nlm.nih.gov/pubmed/30947287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214847 |
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