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Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

The inefficient clearance of dying cells can lead to abnormal immune responses, such as unresolved inflammation and autoimmune conditions. We show that tumor suppressor p53 controls signaling-mediated phagocytosis of apoptotic cells through its target, Death Domain1α (DD1α), which suggests that p53...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Science
मुख्य लेखकों: Yoon, Kyoung Wan, Byun, Sanguine, Kwon, Eunjeong, Hwang, So-Young, Chu, Kiki, Hiraki, Masatsugu, Jo, Seung-Hee, Weins, Astrid, Hakroush, Samy, Cebulla, Angelika, Sykes, David B., Greka, Anna, Mundel, Peter, Fisher, David E., Mandinova, Anna, Lee, Sam W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215039/
https://ncbi.nlm.nih.gov/pubmed/26228159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1261669
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