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FGF21 improves glucose homeostasis in an obese diabetes-prone mouse model independent of body fat changes

AIMS/HYPOTHESIS: Fibroblast growth factor 21 (FGF21) is considered to be a promising therapeutic candidate for the treatment of type 2 diabetes. However, as FGF21 levels are elevated in obese and diabetic conditions we aimed to test if exogenous FGF21 is sufficient to prevent diabetes and beta cell...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Laeger, Thomas, Baumeier, Christian, Wilhelmi, Ilka, Würfel, Josefine, Kamitz, Anne, Schürmann, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448882/
https://ncbi.nlm.nih.gov/pubmed/28770320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4389-x
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