Deficiency in plasmacytoid dendritic cells and type I interferon signalling prevents diet-induced obesity and insulin resistance in mice

AIMS/HYPOTHESIS: Obesity is associated with glucose intolerance and insulin resistance and is closely linked to the increasing prevalence of type 2 diabetes. In mouse models of diet-induced obesity (DIO) and type 2 diabetes, an increased fat intake results in adipose tissue expansion and the secreti...

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Publicado en:Diabetologia
Autores principales: Hannibal, Tine D., Schmidt-Christensen, Anja, Nilsson, Julia, Fransén-Pettersson, Nina, Hansen, Lisbeth, Holmberg, Dan
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448810/
https://ncbi.nlm.nih.gov/pubmed/28660492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4341-0
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