The immunomodulatory quinoline-3-carboxamide paquinimod reverses established fibrosis in a novel mouse model for liver fibrosis

Quinoline-3-carboxamides (Q substances) are small molecule compounds with anti-inflammatory properties. In this study, we used one of these substances, Paquinimod, to treat a novel model for chronic liver inflammation and liver fibrosis, the NOD-Inflammation Fibrosis (N-IF) mouse. We show that treat...

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Vydáno v:PLoS One
Hlavní autoři: Fransén Pettersson, Nina, Deronic, Adnan, Nilsson, Julia, Hannibal, Tine D., Hansen, Lisbeth, Schmidt-Christensen, Anja, Ivars, Fredrik, Holmberg, Dan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124744/
https://ncbi.nlm.nih.gov/pubmed/30183741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203228
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