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A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

Here we characterize a new animal model that spontaneously develops chronic inflammation and fibrosis in multiple organs, the non-obese diabetic inflammation and fibrosis (N-IF) mouse. In the liver, the N-IF mouse displays inflammation and fibrosis particularly evident around portal tracts and centr...

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Veröffentlicht in:PLoS One
Hauptverfasser: Fransén-Pettersson, Nina, Duarte, Nadia, Nilsson, Julia, Lundholm, Marie, Mayans, Sofia, Larefalk, Åsa, Hannibal, Tine D., Hansen, Lisbeth, Schmidt-Christensen, Anja, Ivars, Fredrik, Cardell, Susanna, Palmqvist, Richard, Rozell, Björn, Holmberg, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956255/
https://ncbi.nlm.nih.gov/pubmed/27441847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159850
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