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MDM2 and Mitochondrial Function: One Complex Intersection
Decades of research reveal that MDM2 participates in cellular processes ranging from macro-molecular metabolism to cancer signaling mechanisms. Two recent studies uncovered a new role for MDM2 in mitochondrial bioenergetics. Through the negative regulation of NDUFS1 (NADH:ubiquinone oxidoreductase 7...
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| Publié dans: | Biochem Pharmacol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448155/ https://ncbi.nlm.nih.gov/pubmed/30391206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.10.032 |
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