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Somatic alterations of TP53, ERBB2, PIK3CA and CCND1 are associated with chemosensitivity for breast cancers

The correlation of genetic alterations with response to neoadjuvant chemotherapy (NAC) has not been fully revealed. In this study, we enrolled 247 breast cancer patients receiving anthracycline‐taxane‐based NAC treatment. A next generation sequencing (NGS) panel containing 36 hotspot breast cancer‐r...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Yang, Libo, Ye, Feng, Bao, Longlong, Zhou, Xiaoyan, Wang, Zhe, Hu, Peizhen, Ouyang, Nengtai, Li, Xiaojuan, Shi, Yi, Chen, Gang, Xia, Peiyi, Chui, Meiying, Li, Wencai, Jia, Ying, Liu, Yueping, Liu, Junjun, Ye, Junyi, Zhang, Zhe, Bu, Hong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447848/
https://ncbi.nlm.nih.gov/pubmed/30776175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13976
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