Somatic alterations of TP53, ERBB2, PIK3CA and CCND1 are associated with chemosensitivity for breast cancers

The correlation of genetic alterations with response to neoadjuvant chemotherapy (NAC) has not been fully revealed. In this study, we enrolled 247 breast cancer patients receiving anthracycline‐taxane‐based NAC treatment. A next generation sequencing (NGS) panel containing 36 hotspot breast cancer‐r...

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Vydáno v:Cancer Sci
Hlavní autoři: Yang, Libo, Ye, Feng, Bao, Longlong, Zhou, Xiaoyan, Wang, Zhe, Hu, Peizhen, Ouyang, Nengtai, Li, Xiaojuan, Shi, Yi, Chen, Gang, Xia, Peiyi, Chui, Meiying, Li, Wencai, Jia, Ying, Liu, Yueping, Liu, Junjun, Ye, Junyi, Zhang, Zhe, Bu, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447848/
https://ncbi.nlm.nih.gov/pubmed/30776175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13976
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