Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue

Background: Many forms of hypertrophic cardiomyopathy (HCM) show an increased myofilament Ca(2+) sensitivity. This observation has been mainly made in HCM mouse models, myofilament systems, and cardiomyocytes. Studies of multicellular tissues from patients with different HCM-associated gene mutation...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Kresin, Nico, Stücker, Sabrina, Krämer, Elisabeth, Flenner, Frederik, Mearini, Giulia, Münch, Julia, Patten, Monica, Redwood, Charles, Carrier, Lucie, Friedrich, Felix W.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447666/
https://ncbi.nlm.nih.gov/pubmed/30984009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00239
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