The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based Inhibitors

Epoxide hydrolases (EHs) are enzymes involved in the metabolism of endogenous and exogenous epoxides, and the development of EH inhibitors has important applications in the medicine. In humans, EH inhibitors are being tested in the treatment of cardiovascular diseases and show potent anti-inflammato...

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Библиографические подробности
Опубликовано в: :Int J Biol Macromol
Главные авторы: de Oliveira, Gabriel S., Adriani, Patricia P., Ribeiro, João Augusto, Morisseau, Christophe, Hammock, Bruce D., Dias, Marcio Vinicius B., Chambergo, Felipe S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447457/
https://ncbi.nlm.nih.gov/pubmed/30771398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2019.02.070
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