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Mitochondrial AAA‐ATPase Msp1 detects mislocalized tail‐anchored proteins through a dual‐recognition mechanism

The conserved AAA‐ATPase Msp1 is embedded in the outer mitochondrial membrane and removes mislocalized tail‐anchored (TA) proteins upon dysfunction of the guided entry of tail‐anchored (GET) pathway. It remains unclear how Msp1 recognizes its substrates. Here, we extensively characterize Msp1 and it...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Li, Lanlan, Zheng, Jing, Wu, Xi, Jiang, Hui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446203/
https://ncbi.nlm.nih.gov/pubmed/30858337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846989
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