Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

The majority of ER-targeted tail-anchored (TA) proteins are inserted into membranes by the Guided Entry of Tail-anchored protein (GET) system. Disruption of this system causes a subset of TA proteins to mislocalize to mitochondria. We show that the AAA+ ATPase Msp1 limits the accumulation of misloca...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Yu-Chan, Umanah, George K E, Dephoure, Noah, Andrabi, Shaida A, Gygi, Steven P, Dawson, Ted M, Dawson, Valina L, Rutter, Jared
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198051/
https://ncbi.nlm.nih.gov/pubmed/24843043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201487943
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados