Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions

During development of pancreatic cancer, alternatively-activated macrophages contribute to fibrogenesis, pancreatic intraepithelial neoplasia (PanIN) lesion growth, and generation of an immunosuppressive environment. Here we show that the immunomodulatory agent pomalidomide depletes pancreatic lesio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Res
मुख्य लेखकों: Bastea, Ligia I., Liou, Geou-Yarh, Pandey, Veethika, Fleming, Alicia K., von Roemeling, Christina A., Doeppler, Heike, Li, Zhimin, Qiu, Yushi, Edenfield, Brandy, Copland, John A., Tun, Han W., Storz, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445670/
https://ncbi.nlm.nih.gov/pubmed/30696657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1153
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