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Synthesis and biological evaluation of novel 7-hydroxy-4-phenylchromen-2-one–linked to triazole moieties as potent cytotoxic agents

A new series of novel 7-hydroxy-4-phenylchromen-2-one (1a)–linked 1,2,4-triazoles were synthesised using a click chemistry approach. All derivatives were subjected to 3-(4,5-dimethylthiazol-yl)-diphenyl tetrazolium bromide (MTT) cytotoxicity screening against a panel of six different human cancer ce...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Liu, Chuan-Feng, Shen, Qing-Kun, Li, Jia-Jun, Tian, Yu-Shun, Quan, Zheshan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445224/
https://ncbi.nlm.nih.gov/pubmed/28791908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1344982
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