Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

A diverse set of mono- and bis-sulfonamide was obtained via a direct, chemoselective sulfochlorination of readily available yet hitherto unexplored N-arylpyrazole template. Biochemical profiling of compounds thus obtained against a panel of human carbonic anhydrases (hCA I, hCA II, hCA IV and hCA VI...

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Pubblicato in:J Enzyme Inhib Med Chem
Autori principali: Krasavin, Mikhail, Korsakov, Mikhail, Ronzhina, Oksana, Tuccinardi, Tiziano, Kalinin, Stanislav, Tanç, Muhammet, Supuran, Claudiu T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445164/
https://ncbi.nlm.nih.gov/pubmed/28718328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1344236
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