WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis

WNTs are lipid-modified proteins that control multiple functions in development and disease via short- and long-range signaling. However, it is unclear how these hydrophobic molecules spread over long distances in the mammalian brain. Here we show that WNT5A is produced by the choroid plexus (ChP) o...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Kaiser, Karol, Gyllborg, Daniel, Procházka, Jan, Salašová, Alena, Kompaníková, Petra, Molina, Francisco Lamus, Laguna-Goya, Rocio, Radaszkiewicz, Tomasz, Harnoš, Jakub, Procházková, Michaela, Potěšil, David, Barker, Roger A., Casado, Ángel Gato, Zdráhal, Zbyněk, Sedláček, Radislav, Arenas, Ernest, Villaescusa, J. Carlos, Bryja, Vítězslav
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445127/
https://ncbi.nlm.nih.gov/pubmed/30940800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09298-4
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