Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b

Body and organ size regulation in mammals involves multiple signaling pathways and remains largely enigmatic. Here, we report that Pum1 and Pum2, which encode highly conserved PUF RNA-binding proteins, regulate mouse body and organ size by post-transcriptional repression of the cell cycle inhibitor...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Lin, Kaibo, Qiang, Wenan, Zhu, Mengyi, Ding, Yan, Shi, Qinghua, Chen, Xia, Zsiros, Emese, Wang, Kun, Yang, Xiaodi, Kurita, Takeshi, Xu, Eugene Yujun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444939/
https://ncbi.nlm.nih.gov/pubmed/30811992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.111
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