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Impact of LEDGIN treatment during virus production on residual HIV-1 transcription

BACKGROUND: Persistence of latent, replication-competent provirus is the main impediment towards the cure of HIV infection. One of the critical questions concerning HIV latency is the role of integration site selection in HIV expression. Inhibition of the interaction between HIV integrase and its ch...

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Bibliografske podrobnosti
izdano v:Retrovirology
Main Authors: Vansant, Gerlinde, Vranckx, Lenard S., Zurnic, Irena, Van Looveren, Dominique, Van de Velde, Paulien, Nobles, Christopher, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444612/
https://ncbi.nlm.nih.gov/pubmed/30940165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0472-3
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