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An improved synthesis of adefovir and related analogues
An improved synthesis of the antiviral drug adefovir is presented. Problems associated with current routes to adefovir include capricious yields and a reliance on problematic reagents and solvents, such as magnesium tert-butoxide and DMF, to achieve high conversions to the target. A systematic study...
Gardado en:
| Publicado en: | Beilstein J Org Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Beilstein-Institut
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6444443/ https://ncbi.nlm.nih.gov/pubmed/30992729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.77 |
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