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Doxycycline-inducible and astrocyte-specific HIV-1 Tat transgenic mice (iTat) as an HIV/neuroAIDS model

HIV-1 Tat is known to be neurotoxic and important for HIV/neuroAIDS pathogenesis. However, the overwhelming majority of the studies involved use of recombinant Tat protein. To understand the contributions of Tat protein to HIV/ neuroAIDS and the underlying molecular mechanisms of HIV-1 Tat neurotoxi...

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Bibliografske podrobnosti
izdano v:J Neurovirol
Main Authors: Langford, Dianne, Kim, Byung oh, Zou, Wei, Fan, Yan, Rahimain, Pejman, Liu, Ying, He, Johnny J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444363/
https://ncbi.nlm.nih.gov/pubmed/29143286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-017-0598-9
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