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Activation of Egr-1 expression in astrocytes by HIV-1 Tat: new insights into astrocyte-mediated Tat neurotoxicity

Human immunodeficiency virus type 1 (HIV-1) Tat plays an important role in HIV-associated neuropathogenesis; the underlying mechanisms are still evolving. We have recently shown that HIV-1 Tat induces expression of glial fibrillary acidic protein (GFAP), a characteristic of HIV-1 infection of the ce...

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Autori principali: Fan, Yan, Zou, Wei, Green, Linden A., Kim, Byung oh, He, Johnny J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056338/
https://ncbi.nlm.nih.gov/pubmed/20414733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-010-9217-8
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