Astrocytic metabolic switch is a novel etiology for Cocaine and HIV-1 Tat-mediated neurotoxicity

Calcium (Ca(2+)) dynamics and oxidative signaling control mitochondrial bioenergetics in the central nervous system, where astrocytes are a major energy source for neurons. Cocaine use exacerbates HIV-associated neurocognitive disorders, but little is known about disruptions in astrocyte metabolism...

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發表在:Cell Death Dis
Main Authors: Natarajaseenivasan, Kalimuthusamy, Cotto, Bianca, Shanmughapriya, Santhanam, Lombardi, Alyssa A., Datta, Prasun K., Madesh, Muniswamy, Elrod, John W., Khalili, Kamel, Langford, Dianne
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856787/
https://ncbi.nlm.nih.gov/pubmed/29549313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0422-3
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