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HIV-Tat regulates macrophage gene expression in the context of neuroAIDS

Despite the success of cART, greater than 50% of HIV infected people develop cognitive and motor deficits termed HIV-associated neurocognitive disorders (HAND). Macrophages are the major cell type infected in the CNS. Unlike for T cells, the virus does not kill macrophages and these long-lived cells...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carvallo, Loreto, Lopez, Lillie, Fajardo, Jorge E., Jaureguiberry-Bravo, Matias, Fiser, Andras, Berman, Joan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481010/
https://ncbi.nlm.nih.gov/pubmed/28640909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179882
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