Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-Associated Kinase Activity in Patients With Hypertension

Hypertension is associated with endothelial dysfunction and activated Rho-associated kinases (ROCKs). The purpose of this study was to evaluate the effects of the selective mineralocorticoid receptor blocker, eplerenone, on endothelial function and ROCK activity in patients with hypertension. The st...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Fujimura, N, Noma, K, Hata, T, Soga, J, Hidaka, T, Idei, N, Fujii, Y, Mikami, S, Maruhashi, T, Iwamoto, Y, Kihara, Y, Chayama, K, Kato, H, Liao, JK, Higashi, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444052/
https://ncbi.nlm.nih.gov/pubmed/22205191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.227
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