Calcium Channel Blocker and Rho-associated Kinase Activity in Patients with Hypertension

BACKGROUND: Rho-associated kinases (ROCKs) play an important role in Ca(2+) sensitization and vascular resistance. Activation of ROCKs is associated with hypertension. The purpose of this study was to evaluate the effect of the calcium channel blocker amlodipine on ROCKs activity in patients with hy...

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Main Authors: Hata, Takaki, Soga, Junko, Hidaka, Takayuki, Idei, Naomi, Fujii, Yuichi, Fujimura, Noritaka, Mikami, Shinsuke, Maruhashi, Tatsuya, Kihara, Yasuki, Chayama, Kazuaki, Kato, Hitoshi, Noma, Kensuke, Liao, James K, Higashi, Yukihito
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807090/
https://ncbi.nlm.nih.gov/pubmed/21063203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e328340902d
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