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Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugs

Zika virus (ZIKV) is an emerging pathogen that has been associated with large numbers of cases of severe neurologic disease, including Guillain-Barré syndrome and microcephaly. Despite its recent establishment as a serious global public health concern there are no licensed therapeutics to control th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sáez-Álvarez, Yanira, Arias, Armando, del Águila, Carmen, Agudo, Rubén
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444013/
https://ncbi.nlm.nih.gov/pubmed/30932009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41998-1
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