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Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and found intrinsic links between copy number alterati...

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Dades bibliogràfiques
Publicat a:FEBS Open Bio
Autors principals: Ding, Beichen, Yan, Libin, Zhang, Yucong, Wang, Zhize, Zhang, Yangjun, Xia, Ding, Ye, Zhangqun, Xu, Hua
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443872/
https://ncbi.nlm.nih.gov/pubmed/30984543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12600
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