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Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and found intrinsic links between copy number alterati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Open Bio
Egile Nagusiak: Ding, Beichen, Yan, Libin, Zhang, Yucong, Wang, Zhize, Zhang, Yangjun, Xia, Ding, Ye, Zhangqun, Xu, Hua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443872/
https://ncbi.nlm.nih.gov/pubmed/30984543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12600
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