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Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer

Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and found intrinsic links between copy number alterati...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Ding, Beichen, Yan, Libin, Zhang, Yucong, Wang, Zhize, Zhang, Yangjun, Xia, Ding, Ye, Zhangqun, Xu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443872/
https://ncbi.nlm.nih.gov/pubmed/30984543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12600
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