NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies

In contrast to acute peripheral nerve injury, the molecular response of Schwann cells in chronic neuropathies remains poorly understood. Onion bulb structures are a pathological hallmark of demyelinating neuropathies, but the nature of these formations is unknown. Here, we show that Schwann cells in...

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Publicado no:Nat Commun
Main Authors: Fledrich, Robert, Akkermann, Dagmar, Schütza, Vlad, Abdelaal, Tamer A., Hermes, Doris, Schäffner, Erik, Soto-Bernardini, M. Clara, Götze, Tilmann, Klink, Axel, Kusch, Kathrin, Krueger, Martin, Kungl, Theresa, Frydrychowicz, Clara, Möbius, Wiebke, Brück, Wolfgang, Mueller, Wolf C., Bechmann, Ingo, Sereda, Michael W., Schwab, Markus H., Nave, Klaus-Armin, Stassart, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443727/
https://ncbi.nlm.nih.gov/pubmed/30931926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09385-6
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