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Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13
The interaction between K48-linked ubiquitin (Ub) chain and Rpn13 is important for proteasomal degradation of ubiquitinated substrate proteins. Only the complex structure between the N-terminal domain of Rpn13 (Rpn13(NTD)) and Ub monomer has been characterized, while it remains unclear how Rpn13 spe...
Shranjeno v:
| izdano v: | Cell Discov |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443662/ https://ncbi.nlm.nih.gov/pubmed/30962947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-019-0089-7 |
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