The Small Conductance Calcium Activated Potassium Current Modulates the Ventricular Escape Rhythm in Normal Rabbit Hearts

BACKGROUND: The apamin-sensitive small-conductance calcium-activated K (SK) current (I(KAS)) modulates automaticity of the sinus node; I(KAS) blockade by apamin causes sinus bradycardia. OBJECTIVE: To test the hypothesis that I(KAS) modulates ventricular automaticity. METHODS: We tested the effects...

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Publicado en:Heart Rhythm
Autores principales: Wan, Juyi, Chen, Mu, Wang, Zhuo, Everett, Thomas H., Rubart-von der Lohe, Michael, Shen, Changyu, Qu, Zhilin, Weiss, James N., Boyden, Penelope A., Chen, Peng-Sheng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443460/
https://ncbi.nlm.nih.gov/pubmed/30445170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.10.033
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