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Bub1—the zombie protein that CRISPR cannot kill
The conserved Bub1 kinase was proposed to be non‐essential for the mitotic spindle assembly checkpoint based on recent findings that knocking‐out Bub1 by CRISPR/Cas9 did not impair checkpoint function in human cells. New studies now demonstrate that CRISPR/Cas9 Bub1 knockout cells still express low...
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| Publicado en: | EMBO J |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443206/ https://ncbi.nlm.nih.gov/pubmed/30850387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101912 |
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