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Bub1—the zombie protein that CRISPR cannot kill

The conserved Bub1 kinase was proposed to be non‐essential for the mitotic spindle assembly checkpoint based on recent findings that knocking‐out Bub1 by CRISPR/Cas9 did not impair checkpoint function in human cells. New studies now demonstrate that CRISPR/Cas9 Bub1 knockout cells still express low...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awdur: Meraldi, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443206/
https://ncbi.nlm.nih.gov/pubmed/30850387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101912
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