Zombies Never Die: The Double Life Bub1 Lives in Mitosis

When eukaryotic cells enter mitosis, dispersed chromosomes move to the cell center along microtubules to form a metaphase plate which facilitates the accurate chromosome segregation. Meanwhile, kinetochores not stably attached by microtubules activate the spindle assembly checkpoint and generate a w...

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Detalhes bibliográficos
Main Authors: Yuqing Zhang, Chunlin Song, Lei Wang, Hongfei Jiang, Yujing Zhai, Ying Wang, Jing Fang, Gang Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
mitosis
spindle assembly checkpoint
kinetochore
Bub1
chromosome alignment
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2022.870745/full
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