The sympathomimetic agonist mirabegron did not lower JAK2-V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with myeloproliferative neoplasms: results of phase II study SAKK 33/14

The β-3 sympathomimetic agonist BRL37344 restored nestin-positive cells within the stem cell niche, and thereby normalized blood counts and improved myelofibrosis in a mouse model of JAK2-V617F-positive myeloproliferative neoplasms. We therefore tested the effectiveness of mirabegron, a β-3 sympatho...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Haematologica
Main Authors: Drexler, Beatrice, Passweg, Jakob R., Tzankov, Alexandar, Bigler, Martin, Theocharides, Alexandre PA, Cantoni, Nathan, Keller, Peter, Stussi, Georg, Ruefer, Axel, Benz, Rudolf, Favre, Geneviève, Lundberg, Pontus, Nienhold, Ronny, Fuhrer, Andrea, Biaggi, Christine, Manz, Markus G., Bargetzi, Mario, Mendez-Ferrer, Simon, Skoda, Radek C.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442970/
https://ncbi.nlm.nih.gov/pubmed/30409796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.200014
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki