Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort

Abstract Background/purpose Recently, the mutational background of diffuse large B cell lymphoma (DLBCL) has been revealed, identifying specific genetic events that drive lymphomagenesis. However, the prognostic value of these mutations remains to be determined. Prognostic biomarkers in DLBCL are ur...

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Detalhes bibliográficos
Main Authors: Darius Juskevicius, David Jucker, Dirk Klingbiel, Christoph Mamot, Stephan Dirnhofer, Alexandar Tzankov
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-03-01
Colecção:Journal of Hematology & Oncology
Assuntos:
DLBCL
Prognostic markers
Targeted high-throughput sequencing
NGS
Lymphoma
CREBBP
Acesso em linha:http://link.springer.com/article/10.1186/s13045-017-0438-7
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